Purification and Processing

Antibody Purification Services

MBS offers a wide range of cGMP purification services.  Antibody purification can be done as an extension of our monoclonal and polyclonal production offerings or as a stand alone service. Based on years of purification experience with a vast number of cell culture supernatant, ascites and serum samples, our purification team has developed optimized protocols to generate high quality antibody in quantities sufficient for early screening studies through large-scale production.

Learn more about our available purification services:

  • Protein A purification of mouse monoclonal cell lines with subclass-optimized binding and elution conditions (read more)

  • Protein A and Protein G purification of polyclonal serum (read more)

  • Immunoaffinity purification of polyclonal antibodies using an immobilized antigen column (read more)

  • Preparative Size Exclusion Chromatography (SEC) to remove residual aggregates, dimers and fragments and isolate monomeric IgG (read more)

  • Low Endotoxin purification to generate purified antibody preparations with low EU/mg endotoxin concentrations
    (read more)

  • MultiPure – library of purified hybridoma supernatants provided in a 96-well plate for early ranking assays (read more)

  • ReadyPure – single milligram quantities of purified, subcloned mAb candidates for early characterization and screening (read more)