New Monoclonal Antibodies to Progesterone

MAB234P and MAB235P, monoclonal antibodies to progesterone, are now ready for sampling. The most accurate formats for measurement of progesterone in clinical samples are competition and/or inhibition assays since the molecule is only 314 daltons. Progesterone in a clinical sample competes with a carefully chosen conjugated progesterone reagent for available binding sites on a capture antibody specific for progesterone. The signal seen in a competitive immunoassay is inversely proportional to the amount of progesterone present in a sample. Progesterone Molecular Structure and Numbering of Positions   MAB234P – Generated using progesterone-6-KLH immunogen MAB235P – Generated using progesterone-11-KLH immunogen   A successful,
Read More

Categories: New Products and News.

Stability of Antibody Service Providers

Amid a wave of acquisitions and outsourced manufacturing by antibody service providers, MBS wants to reassure our customers that they can count on the stability and longevity of our organization.  MBS has been privately owned and operated in New England since 1990.  We have stayed true to our core proficiency and quality standards in antibody development, while continuously striving to add to our expertise and tools to assure the highest quality project outcomes. The cornerstones of our success have always been customer communication and in-house project management. Investing in our technical capabilities to meet evolving customer needs signals our commitment
Read More

Categories: New Products, News, and Services.

Antibodies to Lactoferrin

MBS is now offering two antibodies specific for lactoferrin, MAB232P, and MAB233P.  Lactoferrin is part of the transferrin family of proteins, an iron binding glycoprotein involved in host defense against infection and is a modulator of inflammatory reactions.    The antibodies were evaluated for their ability to work as matched pairs in a mono-mono sandwich ELISA format. Biotin conjugates of both antibodies were prepared for use as tracers. The antibodies demonstrated the ability to work in both capture/tracer configurations. Both monoclonal antibodies were evaluated by indirect ELISA and sandwich ELISA (data not shown) for cross-reactivity to transferrin, both Apo (iron-free)
Read More

Categories: New Products and News.

New Recombinant Tag Antibodies

Monoclonal Antibody to Polyhistidine (HIS)-tag MAB230P, a monoclonal antibody specific for the polyhistidine (HIS) tag, is part of a growing list of MBS products aimed at assisting our customers in the detection of recombinant proteins.  HIS-tag is the most popular recombinant protein tag and MAB230P is being widely sampled and used by customers with need for a high affinity, highly specific HIS-tag antibody.  MBS R&D developed the murine antibody using 6X-His-KLH.  The internal development and production of MAB230P allows MBS to maintain the highest quality standards and the ability to offer the lowest possible price. MAB230P Quantity/Price: 100ug $200 | 1mg
Read More

Categories: New Products and News.

Assay Development Services

In response to customer inquiries, MBS announces the expansion of contract services offered to include ELISA development.  The assay development service will provide customers with refined, R&D use assays at the end of hybridoma development.   Optimization of reagents for assay applications has long been an area of core competency for MBS, used heavily in the development of internal products and services. It is with great excitement that we will, for the first time, be extending the benefit of that experience to our hybridoma development customers.   Included in the service will be the development of an optimized ELISA using your predicted
Read More

Categories: New Products, News, and R&D Updates.

Development of New Antibodies to Norovirus

Monoclonal Antibodies to Human Norovirus GI and GII Maine Biotechnology Services developed a comprehensive panel of antibodies specific for human Norovirus, including GII.4 2012 Sydney strain.  MAB223P through MAB228P have been tested across a broad range of strains, as reported in the table below.  In addition to being broadly cross reactive to GII.4 genotypes, MAB227P has demonstrated the ability to block ligand binding in surrogate neutralization assays.  MAB228P, developed against GI.1 1968 virus like particles (VLPs), has been shown to recognize additional GI types.  There are currently five known genogroups, of which three cause human disease: GI, GII, and GIV.
Read More

Categories: New Products, News, and R&D Updates.

Isotype Control and Secondary Antibodies

MBS now offers comprehensive panels of isotype control and secondary antibodies, developed in house, for maximum cost and supply flexibility. Secondary Antibodies Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of target antigens. To ensure detection, the secondary antibody must be specific for the antibody species and isotype of the primary antibody in the application. Currently we are offering secondary anti-human antibodies to Fc, IgA, IgM, IgG1, IgG2, IgG3, IgG4, Kappa, and Lambda isotypes.     Isotype Control Antibodies Selecting a functional isotype control is a critical step in many laboratory experiments, particularly flow
Read More

Categories: New Products and News.

Antibodies to Human Myeloperoxidase

Developed by MBS R&D – MAB208P and MAB209P Recognize native human myeloperoxidase Antibodies work as a matched pair in a sandwich ELISA Do not cross-react with human lactoferrin or bovine lactoperoxidase Outperform current gold standard in flow cytometry applications  Product Datasheets MAB208P MAB209P Related Research News on Myeloperoxidase in research, MBS has new clones specific for human MPOhttp://www.ncbi.nlm.nih.gov/pubmed/17592500                        
Read More

Categories: New Products and News.