GST Monoclonal Antibody – Glutathione S-transferase

MAB241P, a monoclonal antibody specific for GST-tag, is part of a growing list of MBS products aimed at assisting our customers in the detection of recombinant proteins.  MBS R&D developed the murine antibody using recombinant GST as an immunogen.  MAB241P was shown to recognize N or C terminal GST fusion proteins as well as recombinant GST protein in Western Blot.  The internal development and production of MAB241P allows MBS to maintain the highest quality standards and the ability to offer the lowest possible price. Buy MAB241P       • Applications: Validated in western blot • Reactivity: Recognizes free GST, C
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Categories: New Products and News.

Food poisoning? It was likely a restaurant worker, says CDC – The Chart – CNN.com Blogs

Food poisoning? It was likely a restaurant worker, says CDC Approximately 20 million people fall ill every year due to norovirus, according to a new report from the Centers for Disease Control and Prevention, which says the food service industry could do much to decrease that number. Restaurants and catering services are the most common sources for norovirus outbreaks from contaminated food, according to the report. “Infected food workers are frequently the source of these outbreaks, often by touching ready-to-eat foods served in restaurants with their bare hands,” CDC experts wrote. Norovirus is the most common cause of acute gastroenteritis
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Categories: New Products and News.

E. coli Recombinant Antigen Expression Now Available

Antigen Sequence to Monoclonal Antibody For 25 years, Maine Biotechnology Services has been a leading provider of quality antibody reagents in both research and diagnostic fields.  MBS has long been able to leverage internal custom antibody service expertise to design, develop, and support the highest quality antibodies at affordable prices.  Three years ago, MBS built a new lab and dedicated research and development scientists to the endeavor of adding recombinant protein production capabilities to the MBS skill set.  After a year of R&D, MBS began to regularly use internal recombinant antigen production to support antibody product development.  Many of the
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Categories: New Products, News, and Services.

MBS at BIO and AACC 2014

MBS will be attending BIO International Convention in San Diego, California June 23rd-26th.  We will also be exhibiting at AACC booth #3748 in Chicago, Illinois July 29th-31st.  Meet with MBS Sales representatives to learn more about our growing service and product catalogs.  2014 is an exciting year at MBS as we roll out the long awaited additions of recombinant antigen production services as well as early assay development work to our established antibody development and production core services.  MBS is now proud to deliver recombinant antigens developed with hybridoma development and customer end uses in mind, fully characterized purified antibodies,
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Categories: New Products, News, Services, and Upcoming Events.

Chikungunya now an epidemic in the Caribbean

Chikungunya now an epidemic in the Caribbean                                        Thursday, May 01, 2014 | 2:07 PM      ORANJESTAD, Aruba (CMC) – The head of the Caribbean Public Health Authority (CARPHA), Dr James Hospedales, has declared the Chikungunya virus has reached epidemic proportions in the Caribbean. “By definition this is an epidemic since it represents an unusual number of cases of this problem where we would never have it before,” Dr Hospedales told the Caribbean Media Corporation (CMC). The mosquito-borne illness was first
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Categories: New Products and News.

MBS-USDA Rift Valley Fever Virus Partnership

Two monoclonal antibodies to the nucleocapsid protein of Rift Valley Fever Virus (RVFV), MAB239P and MAB240P, are now available for sampling from MBS R&D. The clones are a result of a partnership between MBS and the USDA-Agricultural Research Service  (USDA-ARS) to develop detection reagents for RVFV assays. For this project, mice were immunized with RVFV lysates and screened for recognition of recombinant nucleocapsid protein (rNP). A sandwich ELISA against rNP demonstrated a sensitivity level of at least 6 ng/ml.  The clones were then screened by USDA-ARS by indirect ELISA against native virus to confirm specificity.  In the final phase of
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Categories: New Products, News, and R&D Updates.

MBS Sales Director Interviewed in Drug Development and Delivery: Early-Stage Partnerships Are On The Rise

MAINE BIOTECHNOLOGY SERVICES—SPECIALIZING IN ANTI-ID SCREENING MBS provides monoclonal and polyclonal antibody services, from design and development to production, characterization, and assay development. MBS works with both pharmaceutical and diagnostic companies to develop antibodies against their targets of interest, which may include small molecules, recombinant antigens, peptides, and anti-idiotypes. Tools such as MultiPure technology and Octet Red kinetic analysis are used to allow customers the opportunity to refine their clone selection earlier in the process. The antibodies developed by MBS are used by customers to support therapeutic product release and clinical trials, as well as within their 510K-approved diagnostic kits. 
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Categories: New Products, News, R&D Updates, and Services.

Anti-HIS tag Antibody from MBS Incorporated into ForteBio Dip and Read Anti-HIS (HIS2) Biosensors

Portland Maine –  MBS MAB230P, monoclonal antibody to the polyhistidine (HIS) tag has been incorporated into the second generation Forte Bio Anti-HIS biosensors for rapid quantitative measurement of HIS tagged proteins.  MAB230P was selected by ForteBio after demonstrating high specificity and excellent sensitivity, detecting HIS tagged proteins in nanogram quantities.  The antibody is broadly reactive, recognizing HIS tags of 4X or greater, engineered at either the N- or C-terminus of the protein. The internal development and production of MAB230P allows MBS to maintain the highest quality standards and the ability to offer the lowest price in the marketplace.  The MAB230P
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Categories: New Products, News, and Press Releases.

MBS-USDA Partnership Provides Monoclonal Antibodies to Aid in the Containment of Rift Valley Fever Virus

Portland, Maine- In July 2012, Maine Biotechnology Services entered into a partnership with Dr. Scott McVey, supervisor of the USDA-Agricultural Research Service  (USDA-ARS) Arthropod Borne Animal Disease Research Unit, with the objective of developing monoclonal antibodies to support ongoing research efforts to advance adequate vaccine and rapid detection methods for Rift Valley Fever Virus in Africa. MBS is announcing the release of the first two antibodies resulting from that partnership; a functioning matched pair demonstrating specificity to the nucleocapsid protein of the virus. These antibodies have applications as detection reagents for circulating antigen, mosquito carriers, or as components of differentiation
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Categories: News and Press Releases.

Antibody Purity – How Pure is Pure Enough?

MBS has long used Protein A with pH gradient elution for the purification of murine monoclonal IgG antibodies.  By providing the gentlest conditions possible we have been able to offer our customers consistent monomer IgG purity of ~95%.  When circumstances warrant, we also offer the highest quality standards in Protein G and Immunoaffinity Chromatography techniques.  Increasingly, however, our custom antibody development customers have therapeutic research goals that may require an even higher level of antibody purity.    To meet those customer’s needs, MBS is now offering an additional Size Exclusion Chromatography polishing step to be added to one of our
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Categories: New Products, News, R&D Updates, and Services.